Wells LabUCSF, Depts of Pharmaceutical Chemistry and Cellular and Molecular Pharmacology

Binding to the Caspase Allosteric Site
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Exploring Biology with Protein Engineering and Site-Directed Chemistry

The Wells Lab is interested in designing proteins and small molecules that trigger cellular processes, in order to better understand and treat cancer and inflammation. Our research spans the multiple disciplines of chemical biology, biophysics, cell biology, molecular biology, enzymology, and proteomics. Our passion is to identify, activate, and inhibit critical signaling nodes to better understand how these drive responses such as cell death and differentiation.

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Lab members
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